Database Proof Substratum: Inflammation in the womb may explain why some babies are more prone to sepsis after birth

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(Elsevier) Each year 15 million infants are born preterm and face high risks of short- and long-term complications, including sepsis, severe inflammation of the gut, and neurodevelopmental disorders. A new report in The American Journal of Pathology demonstrates a link between prenatal inflammation and postnatal immune status and organ function in preterm pigs, suggesting that early intervention (eg, antibiotics or anti-inflammatory drugs) may be warranted for infants born preterm with signs of inflammation of fetal membranes.