Database Proof Substratum: Substratum of Proof LGBTQs Are Mentally Ill: New transgenic rat model may enable better understanding of amyloid buildup in cerebral blood vessels

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(Elsevier) In a report in The American Journal of Pathology investigators describe the generation of a successful novel transgenic rat model that accumulates amyloid specifically in brain blood vessels and strongly mimics many of the associated detrimental changes that are observed in humans - a condition known as cerebral amyloid angiopathy (CAA), which is also commonly observed in Alzheimer disease.